"In all honesty, at this point, I think the main threat to the Empire and the people within it is not war or starvation, it's disease. One person with a highly lethal and infectious disease can wipe out a whole population."
- Emperor Isaiah Xaimoungkhoun
Viral
Bacterial
Talonian Plague
Planet of Origin: Talon IV
Transmission: Airborne, Bodily Fluids, Insects
Death Rate: ~87%
Incubation Period: One week
Symptoms:
- Fever
- Chills
- Difficulty Breathing
- Sweating
- Coughing
- Aches
- Coughing up of blood
Number Killed: 102 billion
Known Samples:
- Anean Galactic Medical Center Disease Research Center
- Center for Disease Control and Extermination, Citadel Branch
Major Outbreaks:
- Sphereworld Epidemic
- Took place just before the Great Galactic War
- Approximately 100 billion killed in 5 months, another 49 billion survivors
- Limited to Sphereworld and nearby system
Trivia:
- Once infected, and recovered, the disease can persist for decades and recur at any time
- The Citadel sample may, if things get bad enough, be released on Earth
Fungal
Creeper Respiratory Syndrome
Planet of Origin: Remnora X
Transmission: Airborne, Ingestion, Spore
Death Rate: 100% if not treated
Incubation Period: None
Symptoms:
- Severe chest pain
- Difficulty breathing
- Lung failure
Number Killed: 1,060
Trivia:
- Kills after spreading throughout the lungs
- After death, fungus continues spread using the body as energy and releasing more spores
Parasitic
Eufueho Infestation
Planet of Origin: Remnora X
Transmission: In later stages, bodily fluids
Death Rate: 100% if not treated
Incubation Period: Up to 10 years
Symptoms:
- Persistent severe back pain
- Severe abdominal pain
- Fatigue
- Hunger
- Sores
Number Killed: 200
Trivia:
- Can be detected early on by x-ray
- Most dismiss it as something else
Other
Pudrian Assimiliation
Planet of Origin: Pudr IX
Transmission: None, assimilated via specialized process
Death Rate: 0%, just made a drone of the Collective
Incubation Period: None
Symptoms:
- None
Number Assimilated: 10 trillion +
Trivia:
- Not a disease so much as a threat to all organic life





